Hyaluronic acid is one of the main components of the connective tissue. It is a voluminous molecule greedy for water that is able to bind a large number of molecules and therefore represents a water reservoir for the tissue where it is normally found.

At the level of the skin, this characteristic can translate into greater resistance and an increase in turgor. It also has the ability to stimulate collagen production as well as manifesting cicatricial and anti-inflammatory properties.

These characteristics have favored its use in the cosmetic industry. Hyaluronic acid (with high molecular weight or high MW) was initially used as it was found in nature but it has been seen that it crossed the skin barrier with some difficulty given its considerable size. After application, remaining largely on the surface of the epidermis, this molecule still maintains the characteristic of binding water and therefore its moisturizing capacity is exploited to counteract surface dryness.

Later it was used for micro-injections (fillers) for aesthetic purposes. In this way, hyaluronic acid is released directly into the dermis where it can perform its action. At this level, swelling with water like a sponge, it creates thickness under the folds of the skin, relaxing its surface features.

Recently it has been possible to deepen its cosmetic use by dividing this large molecule into several parts so that they can more easily pass the skin barrier while maintaining the original properties. It has even been hypothesized that these smaller molecules, called low molecular weight (low MW), can serve as a template for the generation of new hyaluronic acid by the dermis.

Its wide use is also justified by the fact that, except in rare cases of hypersensitivity, hyaluronic acid is free from side effects and contraindications.

Originally obtained from the rooster’s combs, hyaluronic acid on the market is currently produced in the laboratory through bacterial fermentation.

INCI: Hydrolysed Hyaluronic Acid

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